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CYP11B2 / Aldosterone Synthase

cytochrome P450, family 11, subfamily B, polypeptide 2

CYP11B2 / Aldosterone Synthase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Gene Name: cytochrome P450, family 11, subfamily B, polypeptide 2
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP11B2, ALDOS, Aldosterone synthase, CYP11BL, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, P-450C18, p450aldo, Steroid 18-hydroxylase, Steroid 11-beta-monooxygenase, CYP11B, p450C18, Steroid 11-beta/18-hydroxylase
Target Sequences: NM_000498 NP_000489.3 P19099

☰ Filters
Antibodies (18)
Proteins (4)
ELISA Kits (3)
Over-Expression Lysate (2)
Primary (18)
Recombinant (2)
Sandwich (3)
CYP11B2 / Aldosterone Synthase (25)
Human (18)
Mouse (8)
Rat (6)
IHC (7)
IHC-P (1)
WB (13)
Flo (1)
ELISA (8)
ICC (1)
IF (2)
Peptide-ELISA (1)
rabbit (17)
mouse (1)
IgG (14)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (17)
96-Well Microplate (1)
96-Well Strip Plate (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (12)
C-Terminus (4)
Internal (1)
aa120-147 (1)
aa175-192 (1)
No (24)
Yes (1)
Cell Lysates (2)
Plasma (1)
Serum (1)
Tissue Homogenates (3)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Yeast (1)
Purified (2)
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CYP11B2 / Aldosterone Synthase Mouse anti-Rat Monoclonal (aa175-192) Antibody
Rat
ELISA, ICC, IHC, IHC-P, WB
Unconjugated
500 µl/$786
CYP11B2 / Aldosterone Synthase Antibody - CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CYP11B2 / Aldosterone Synthase Antibody - CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
CYP11B2 / Aldosterone Synthase Antibody - CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
CYP11B2 / Aldosterone Synthase Antibody - CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
CYP11B2 / Aldosterone Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
CYP11B2 / Aldosterone Synthase Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP11B2 / Aldosterone Synthase Antibody - Western blot of CYP11B2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (aa120-147) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated
200 µl/$734
CYP11B2 / Aldosterone Synthase Antibody - Immunohistochemistry of paraffin-embedded Rat adrenal gland using CYP11B2 Polyclonal Antibody at dilution of 1:100 (40x lens).
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CYP11B2 / Aldosterone Synthase Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using CYP11B2 Polyclonal Antibody at dilution of 1:70(×200)
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CYP11B2 / Aldosterone Synthase Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using CYP11B2 Antibody at dilution of 1:100
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CYP11B2 / Aldosterone Synthase Antibody - Western blot analysis of Cytochrome P450 11B2 expression in HEK293T (A); Raw264.7 (B) whole cell lysates.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$299
CYP11B2 / Aldosterone Synthase Antibody - Western blot analysis of extracts of various cell lines, using CYP11B2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 20s.
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CYP11B2 / Aldosterone Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
CYP11B2 / Aldosterone Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
CYP11B2 / Aldosterone Synthase ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$551
CYP11B2 / Aldosterone Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
57.56 kDa
100 µg/$710
CYP11B2 / Aldosterone Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
57.56 kDa
20 µg/$215
CYP11B2 / Aldosterone Synthase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CYP11B2 / Aldosterone Synthase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$570; 20 µg/$395; 1 mg/$1,973
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).