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CYCS / Cytochrome c

cytochrome c, somatic

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Gene Name: cytochrome c, somatic
Synonyms: CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic
Target Sequences: NM_018947 NP_061820.1 P99999

Publications (3)

1
Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease. She P, Zhang Z, Marchionini D, Diaz WC, Jetton TJ, Kimball SR, Vary TC, Lang CH, Lynch CJ. American journal of physiology. Endocrinology and metabolism. 2011 301:E49-61. [PubMed:21505144] [PMC:PMC3129844] Related Antibodies: LS-C41042.
2
Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species. McGuire KA, Barlan AU, Griffin TM, Wiethoff CM. Journal of virology. 2011 85:10806-13. [PubMed:21835790] [PMC:PMC3187480] Related Antibodies: LS-C41042.
3
Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. Emilie Barruet , Steven M Garcia , Katharine Striedinger, Jake Wu, Solomon Lee, Lauren Byrnes, Alvin Wong, Sun Xuefeng, Stanley Tamaki, Andrew S Brack, Jason H Pomerantz. eLife. 2020 Apr;9:e51576. [Full Text Article] [PubMed:32234209] [PMC:PMC7164960]

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (3)
Recombinant (10)
CYCS / Cytochrome c (13)
No (13)
6His, C-terminus (2)
6His, N-terminus (1)
GST (2)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (4)
TRX-6His, N-terminus (1)
Human (9)
Mouse (2)
293T Cells (1)
E. coli (7)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (2)
Select
E. coli
GST, N-terminus
39.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CYCS / Cytochrome c Protein - Purified recombinant protein CYCS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
11.6 kDa
20 µg/$1,107
CYCS / Cytochrome c Protein - Recombinant Cytochrome C, Somatic By SDS-PAGE
Select
E. coli
His
11.1 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CYCS / Cytochrome c Protein - Recombinant Cytochrome C, Somatic By SDS-PAGE
Select
E. coli
His
12.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.8kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
CYCS / Cytochrome c Protein - 12.5% SDS-PAGE of human CYCS stained with Coomassie Blue
Select
Wheat Germ Extract
GST
37.29 kDa
2 µg/$439
CYCS / Cytochrome c Protein - 12.5% SDS-PAGE of human CYCS stained with Coomassie Blue
Select
Wheat Germ Extract
GST
37.29 kDa
10 µg/$479; 25 µg/$670
CYCS / Cytochrome c Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
11.6 kDa
20 µg/$150
CYCS / Cytochrome c Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
11.6 kDa
100 µg/$494
CYCS / Cytochrome c Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
34.8 kDa
100 µg/$494
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.8 kDa
10 µg/$344; 50 µg/$584
CYCS / Cytochrome c Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
13.9 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
CYCS / Cytochrome c Protein
Select
E. coli
TRX-6His, N-terminus
12 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).