CYBA / p22phox

cytochrome b-245, alpha polypeptide

Cytochrome b is composed of cytochrome b alpha (CYBA; flavocytochrome b-558) and beta (CYBB; flavocytochrome b-245) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBA deficiency is associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

CYBA / p22phox (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CYBA / p22phox Protein (Recombinant GST) (Full Length) - LS-G28122

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.68 kDa

Price:

2 µg/$439

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CYBA / p22phox Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98916

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.8 kDa

Price:

100 µg/$494

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Human CYBA / p22phox Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75388

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.8 kDa

Price:

20 µg/$150

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