CXCR2

chemokine (C-X-C motif) receptor 2

CXCR2 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

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Products

ELISA Kits (14)

Type

Custom (5)

Development Kit (1)

Sandwich (8)

Target

CXCR2 (14)

Reactivity

Human (5)

Mouse (4)

Rat (3)

Dog (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (11)

Antibody Pair and Standard (1)

Publications

No (14)

Sample Type

Cell Lysates (4)

Plasma (7)

Serum (7)

Tissue Homogenates (7)

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Human CXCR2 (Sandwich ELISA) ELISA Kit - LS-F8473

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse CXCR2 (Sandwich ELISA) ELISA Kit - LS-F32109

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse CXCR2 (Sandwich ELISA) ELISA Kit - LS-F23551

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CXCR2 (Sandwich ELISA) ELISA Kit - LS-F5414

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Mouse CXCR2 (Sandwich ELISA) ELISA Kit - LS-F9106

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$748

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Bovine CXCR2 (Custom ELISA) ELISA Kit - LS-F19025

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human CXCR2 (Custom ELISA) ELISA Kit - LS-F19026

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CXCR2 (Custom ELISA) ELISA Kit - LS-F19027

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Dog CXCR2 (Custom ELISA) ELISA Kit - LS-F19028

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse CXCR2 (Custom ELISA) ELISA Kit - LS-F19029

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CXCR2 (Sandwich ELISA) ELISA Kit - LS-F32220

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CXCR2 (Sandwich ELISA) ELISA Kit - LS-F32000

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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DevKit DuoPlus Human CXCR2 ELISA Development Kit - LS-F71511

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

1.562 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,120; 1000 Wells/$1,642

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Human CXCR2 (Sandwich ELISA) ELISA Kit - LS-F22774

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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