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CXCR1
chemokine (C-X-C motif) receptor 1
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
| Gene Name: | chemokine (C-X-C motif) receptor 1 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | CXCR1, C-C, Chemokine c-x-c receptor 1, CKR-1, CMKAR1, CD128, CD181, CD181 antigen, CXCR-1, CXC-R1, IL-8R A, Il8 receptor a, Interleukin 8 receptor a, Interleukin 8 receptor alpha, Interleukin 8 receptor, alpha, Interleukin-8 receptor type A, IL8RBA, Interleukin-8 receptor type 1, C-C-CKR-1, CDw128a, IL-8 receptor type 1, IL8R1, IL8RA |
| Target Sequences: | NM_000634 NP_000625.1 P25024 |
Publications (3)
1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human)
[Full Text Article]
[PubMed:25870011]
[PMC:PMC4623112]
Related Antibodies: LS-C178869.
2
Inflammatory Bowel Disease Types Differ in Markers of Inflammation, Gut Barrier and in Specific Anti-Bacterial Response. Stepan Coufal, Natalie Galanova, Lukas Bajer, Zuzana Gajdarova, Dagmar Schierova, Zuzana Jiraskova Zakostelska, Klara Kostovcikova, Zuzana Jackova, Zuzana Stehlikova, Pavel Drastich, Helena Tlaskalova-Hogenova, Miloslav Kverka. Cells. 2019 Jul;8:719. [Full Text Article]
[PubMed:31337064]
[PMC:PMC6678638]
3
ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Wilson BJ, Saab KR, Ma J, Schatton T, P[Character fc]tz P, Zhan Q, Murphy GF, Gasser M, Waaga-Gasser AM, Frank NY, Frank MH. Cancer research. Aug;74:4196-207. [Full Text Article]
[PubMed:24934811]
[PMC:PMC4119553]
Related Antibodies: LS-A806.
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(16)
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(14)
Yes
(2)
CXCR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
CXCR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
CXCR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CXCR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$332
CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
0.1 mg/$386
CXCR1 Rabbit anti-Human Polyclonal (aa24-38) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CXCR1 Mouse anti-Human Monoclonal (2B8A1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$459
CXCR1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CXCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CXCR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CXCR1 Rabbit anti-Human Polyclonal (aa1-22) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
IP, Peptide-ELISA, WB
Unconjugated
100 µg/$351
CXCR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$357
CXCR1 Goat anti-Human Polyclonal (aa26-38) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
CXCR1 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
WB
Unconjugated, Preservative Free
100 µl/$412
CXCR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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