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Vector Laboratories, Inc.
6737 Mowry Ave
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CXCL7 / PPBP
Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7)
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
| Gene Name: | Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7) |
| Family/Subfamily: | Intercrine , Intercrine alpha |
| Synonyms: | PPBP, Beta-thromboglobulin, B-TG1, Beta-TG, C-X-C motif chemokine 7, CTAP3, CXCL7, CTAP-III, CXC chemokine ligand 7, NAP-2, NAP-2-L1, PBP, LA-PF4, LDGF, SCYB7, Small-inducible cytokine B7, Small inducible cytokine B7, THBGB1, Thrombocidin 2, TC2, TGB, Thrombocidin 1, Thromboglobulin, beta-1, CTAPIII, MDGF, Platelet basic protein, SCAR10, TC1, THBGB |
| Target Sequences: | NM_002704 NP_002695.1 P02775 |
☰ Filters
Products
Proteins
(21)
Type
Over-Expression Lysate
(2)
Recombinant
(19)
Target
CXCL7 / PPBP
(21)
Publications
No
(21)
Tag
6His, C-terminus
(2)
GST
(1)
GST, N-terminus
(1)
His, N-Terminal
(1)
His-GST
(2)
His-T7
(2)
Myc-DDK (Flag)
(3)
Species
Human
(14)
Mouse
(2)
Pig
(1)
Rat
(3)
Source
293T Cells
(1)
E. coli
(14)
HEK 293 Cells
(2)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(9)
Biologically Active
Biologically active
(5)
E. coli
His, N-Terminal
11.2 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.6 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
7.6 kDa
10 µg/$388; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
6.8 kDa
10 µg/$388; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
7.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Wheat Germ Extract
GST
40.3 kDa
10 µg/$479; 25 µg/$670
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
11.3kD
10 µg/$248; 50 µg/$321; 500 µg/$869; 1 mg/$1,203
HEK 293 Cells
Myc-DDK (Flag)
10.2 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
13.89 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
13.89 kDa
20 µg/$150
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
7.6 kDa
20 µg/$360; 100 µg/$728
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
7.6 kDa
10 µg/$372; 1 mg/$2,880
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
10 µg/$432; 1 mg/$4,915
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
11.3 kDa
10 µg/$248; 50 µg/$317
E. coli
None
Less than 0.01 ng/µg (determined by LAL method).
The 62 amino acid recombinant protein has a predicted molecular mass of approximately 6.7 kD. The DTT-reduced and non-reduced protein migrate at approximately 11 and 9 kD by SDS-PAGE respectively. The N-terminal amino acid is Ile.
10 µg/$341; 25 µg/$436
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
E. coli
His-T7
11.9 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His-GST
36.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His-T7
10.4 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His-GST
45.0 kDa
10 µg/$298; 50 µg/$550; 100 µg/$877; 200 µg/$1,076; 1 mg/$2,256; 500 µg/$1,770; 5 mg/$4,385
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product results
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