Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CXCL1 / GRO Alpha

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

GRO Alpha (CXCL1), a small cytokine belonging to the CXC chemokine family, secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. GRO alpha is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. GRO Alpha plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. An initial study in mice showed evidence that GRO alpha decreased the severity of multiple sclerosis and may offer a neuro-protective function.

Gene Name: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL1, C-X-C motif chemokine 1, Fibroblast secretory protein, FSP, GRO1, GROa, Growth-regulated alpha protein, GRO-alpha(1-73), MGSA, MGSA-a, Small inducible cytokine b1, GRO, MGSA alpha, NAP-3, SCYB1
Target Sequences: NM_001511 NP_001502.1 P09341

Publications (6)

1
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFa-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, Yamori T, Shibasaki M, Nomoto A. PloS one. 2015 10:e0119415. (IHC; Human) [Full Text Article] [PubMed:25785838] [PMC:PMC4364666] Related Antibodies: LS-C104351.
2
Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study. Brochu ME, Girard S, Lavoie K, Sébire G. Journal of neuroinflammation. 2011 8:55. (WB; Rat) [Full Text Article] [PubMed:21599903]
3
3'-Sialyllactose as an inhibitor of p65 phosphorylation ameliorates the progression of experimental rheumatoid arthritis. Kang LJ, Kwon ES, Lee KM, Cho C, Lee JI, Ryu YB, Youm TH, Jeon J, Cho MR, Jeong SY, Lee SR, Kim W, Yang S. British journal of pharmacology. 2018 December;175:4295-4309. [Full Text Article] [PubMed:30152858] [PMC:PMC6240131]
4
In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines. Sullivan DP, Bui T, Muller WA, Butin-Israeli V, Sumagin R. Mucosal immunology. 2018 November;11:1571-1581. [Full Text Article] [PubMed:30104624] [PMC:PMC6279495]
5
Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II-induced arthritis. Li ZY, Zhou JJ, Luo CL, Zhang LM. Molecular medicine reports. 2019 November;20:4540-4550. [Full Text Article] [PubMed:31702035] [PMC:PMC6797944]
6
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury. Anna Piotrowska, Ewelina Rojewska, Katarzyna Pawlik, Grzegorz Kreiner, Agata Ciechanowska, Wioletta Makuch, Irena Nalepa, Joanna Mika. Frontiers in immunology. 2019 Sep;10:2198. [Full Text Article] [PubMed:31616413] [PMC:PMC6775284] Related Antibodies: LS-C104778.
more

☰ Filters
Products
ELISA Kits (44)
Custom (1)
Development Kit (6)
Sandwich (29)
Sandwich CLIA (8)
CXCL1 / GRO Alpha (44)
Human (14)
Mouse (13)
Rat (13)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
Product Group
DevKit Core (3)
DevKit DuoPlus (3)
1000 Wells (3)
12 x 8-Well Microstrips (5)
96-Well Microplate (9)
96-Well Strip Plate (24)
Antibody Pair and Standard (3)
No (44)
Cell Culture Supernatants (16)
Cell Lysates (10)
Plasma (36)
Serum (39)
Tissue Homogenates (13)
Urine (1)
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.614 - 150 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$426
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$512
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$582
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
4 - 250 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$562
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CXCL1 / GRO Alpha ELISA Kit
Select
Development Kit
1000 Wells
Human
16 - 1000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
234.4 - 7500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
16 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Rat
16 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$699
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CXCL1 / GRO Alpha ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$925; 1000 Wells/$1,318
CXCL1 / GRO Alpha ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$964; 1000 Wells/$1,383
CXCL1 / GRO Alpha ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,108; 1000 Wells/$1,623
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
CXCL1 / GRO Alpha ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$585
CXCL1 / GRO Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Viewing 1-25 of 44 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).