CXCL1 / GRO Alpha

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

GRO Alpha (CXCL1), a small cytokine belonging to the CXC chemokine family, secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. GRO alpha is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. GRO Alpha plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. An initial study in mice showed evidence that GRO alpha decreased the severity of multiple sclerosis and may offer a neuro-protective function.

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Products

Antibodies (129)

ELISA Kits (44)

Proteins (35)

Type

Custom (1)

Development Kit (6)

Primary (129)

Recombinant (35)

Sandwich (29)

Sandwich CLIA (8)

Target

CXCL1 / GRO Alpha (208)

Reactivity

Human (74)

Mouse (53)

Rat (54)

Bat (1)

Bovine (1)

Chimpanzee (3)

Horse (1)

Monkey (2)

Pig (4)

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Sheep (2)

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IHC (10)

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ELISA (44)

Func (1)

ICC (2)

IF (1)

IP (2)

Neut (6)

Peptide-ELISA (3)

Host

rabbit (91)

mouse (37)

goat (1)

Product Group

DevKit Core (3)

DevKit DuoPlus (3)

IHCPlus (2)

Isotype

IgG (46)

IgG1 (2)

IgG1,k (6)

IgG2a,k (1)

IgG2b (1)

IgG2b,k (8)

Clonality

monoclonal mc (38)

polyclonal pc (91)

Clone

012 (1)

04 (1)

12 (1)

2D7 (1)

7A11 (1)

Format

1000 Wells (3)

12 x 8-Well Microstrips (5)

96-Well Microplate (9)

96-Well Strip Plate (24)

Antibody Pair and Standard (3)

APC (8)

APC Conjugated (11)

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Cy7 Conjugated (8)

FITC Conjugated (16)

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Unconjugated (39)

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Epitope

aa25-96 (32)

aa35-107 (8)

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Internal (1)

Pro88 (1)

aa39-88 (1)

aa98-107 (1)

aa99-107 (1)

Publications

No (206)

Yes (2)

Sample Type

Cell Culture Supernatants (16)

Cell Lysates (10)

Plasma (36)

Serum (39)

Tissue Homogenates (13)

Urine (1)

Tag

6His, C-terminus (5)

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (3)

His, N-Terminal (2)

His-GST (2)

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His-T7 (1)

Species

Human (15)

Mouse (15)

Rat (4)

Source

293F Cells (1)

CHO Cells (1)

E. coli (25)

Human Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (3)

Purification

Purified (16)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (13)

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CXCL1 / GRO Alpha Antibody LS-C104351

(4.0) Rating

(1) Publication(s)

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$356; 100 µg/$396

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CXCL1 / GRO Alpha Antibody (Biotin) LS-C104350

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IHC-plus™ CXCL1 / GRO Alpha Antibody LS-B2843

(4.0) Rating

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, Neut, WB

Format:

Unconjugated

Price:

0.1 mg/$495

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IHC-plus™ CXCL1 / GRO Alpha Antibody (Internal) LS-B14347

(4.0) Rating

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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CXCL1 / GRO Alpha Antibody (aa36-107, clone 7A11) LS-C125418

Antibody:

CXCL1 / GRO Alpha Mouse anti-Human Monoclonal (aa36-107) (7A11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$680

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CXCL1 / GRO Alpha Antibody (Pro88) LS-C177218

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal (Pro88) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CXCL1 / GRO Alpha Antibody (clone 2D7) LS-C139335

Antibody:

CXCL1 / GRO Alpha Mouse anti-Human Monoclonal (2D7) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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Mouse CXCL1 / GRO Alpha (Sandwich ELISA) ELISA Kit - LS-F268

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.614 - 150 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$426

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Human CXCL1 / GRO Alpha (Sandwich ELISA) ELISA Kit - LS-F2646

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Monkey CXCL1 / GRO Alpha (Sandwich ELISA) ELISA Kit - LS-F32127

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Porcine CXCL1 / GRO Alpha (Sandwich ELISA) ELISA Kit - LS-F44727

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human CXCL1 / GRO Alpha Protein (Recombinant) - LS-G137791

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 73 amino acid recombinant protein has a predicted molecular mass of approximately 7.8 kD. The DTT-reduced protein migrates at approximately 10 kD and non-reduced protein migrates at slightly higher than 10 kD by SDS-PAGE. The N-terminal amino acid is

Price:

10 µg/$283; 25 µg/$355; 100 µg/$749; 500 µg/$1,828

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CXCL1 / GRO Alpha Antibody LS-C104778

(4.0) Rating

(1) Publication(s)

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$356; 100 µg/$396

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CXCL1 / GRO Alpha Antibody (Biotin) LS-C104777

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Rat Polyclonal (Biotin) Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

CXCL1 / GRO Alpha Antibody LS-C104609

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$356; 100 µg/$396

Select

CXCL1 / GRO Alpha Antibody (Biotin) LS-C104613

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Mouse Polyclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

CXCL1 / GRO Alpha Antibody LS-C801478

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Mouse CXCL1 / GRO Alpha (Sandwich ELISA) ELISA Kit - LS-F5467

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$512

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CXCL1 / GRO Alpha Antibody (aa36-107) LS-C137618

Antibody:

CXCL1 / GRO Alpha Mouse anti-Human Monoclonal (aa36-107) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$445

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CXCL1 / GRO Alpha Antibody LS-C212186

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CXCL1 / GRO Alpha Antibody (FITC) LS-C212195

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Mouse Polyclonal (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• FITC

• Unconjugated
• FITC

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CXCL1 / GRO Alpha Antibody (HRP) LS-C546503

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Neut, WB

Format:

HRP Conjugated

Price:

100 µl/$860

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CXCL1 / GRO Alpha Antibody (HRP) LS-C541665

Antibody:

CXCL1 / GRO Alpha Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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CXCL1 / GRO Alpha Antibody (Biotin) LS-C521532

Antibody:

CXCL1 / GRO Alpha Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

• HRP
• Biotin

• HRP
• Biotin

Select

CXCL1 / GRO Alpha Antibody (aa25-96) LS-C295614

Antibody:

CXCL1 / GRO Alpha Rabbit anti-Mouse Polyclonal (aa25-96) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$291; 200 µl/$326; 500 µl/$441; 1 ml/$499; 2 ml/$622; 5 ml/$1,067

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