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CXADR

coxsackie virus and adenovirus receptor

Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Gene Name: coxsackie virus and adenovirus receptor
Synonyms: CXADR, CAR4/6, Coxsackie-adenovirus receptor, CVB3-binding protein, CAR, HCAR, HCVADR
Target Sequences: NM_001338 NP_001329.1 P78310

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (13)
CXADR (15)
No (15)
6His, C-terminus (2)
6His, N-terminus (1)
Fc, C-terminus (1)
Fc/His,C-terminus (1)
GST (2)
His (1)
His,C-terminus (1)
His-AVI, C-terminus (1)
His-Fc (1)
His-S (1)
Myc-DDK (Flag) (2)
Human (9)
Mouse (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Human Cells (4)
Mammalian Cells (3)
Wheat Germ Extract (2)
Purified (6)
Low endotoxin level (9)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.08kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
CXADR Protein - Recombinant Coxsackie Virus And Adenovirus Receptor By SDS-PAGE
Select
E. coli
His-S
30.7 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
CXADR Protein
Select
E. coli
6His, N-terminus
100 µg/$361; 500 µg/$739; 20 µg/$261
CXADR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
40.03 kDa
20 µg/$150
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
52 kDa
100 µg/$721
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
25 kDa
50 µg/$721
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
25.7 kDa
100 µg/$721
CXADR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
40.03 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.1 kDa
10 µg/$269; 50 µg/$368
Select
HEK 293 Cells
Fc/His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52 kDa
100 µg/$721
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.6 kDa
100 µg/$721
Select
Mammalian Cells
His-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.7 kDa
20 µg/$416; 100 µg/$910
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
10 µg/$288; 50 µg/$436
CXADR Protein - 12.5% SDS-PAGE of human CXADR stained with Coomassie Blue
Select
Wheat Germ Extract
GST
65.89 kDa
2 µg/$439
CXADR Protein - 12.5% SDS-PAGE of human CXADR stained with Coomassie Blue
Select
Wheat Germ Extract
GST
66.4 kDa
2 µg/$439
Viewing 1-15 of 15 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).