CUBN / Cubilin

cubilin (intrinsic factor-cobalamin receptor)

Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

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Products

ELISA Kits (8)

Type

Custom (2)

Sandwich (6)

Target

CUBN / Cubilin (8)

Reactivity

Human (3)

Mouse (1)

Rat (3)

Dog (1)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Cell Lysates (2)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

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Rat CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F25369

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Human CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F8225

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F38077

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F11245

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Dog CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F11246

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human CUBN / Cubilin (Custom ELISA) ELISA Kit - LS-F20516

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse CUBN / Cubilin (Custom ELISA) ELISA Kit - LS-F20517

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat CUBN / Cubilin (Sandwich ELISA) ELISA Kit - LS-F33691

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$579

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