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CTSW / Cathepsin W, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2.
Gene Name: | cathepsin W |
Family/Subfamily: | Protease , Cysteine C1 |
Synonyms: | CTSW, Cathepsin W, Cathepsin W (lymphopain), Lymphopain, LYPN |
Target Sequences: | NM_001335 NP_001326.2 P56202 |
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