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CTSD / Cathepsin D

cathepsin D

CTSD / Cathepsin D is a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. In Chinese hamster the protein Cathepsin D is encoded by the gene H671_3g9701 (Uniprot G3I4W7).

Gene Name: cathepsin D
Family/Subfamily: Protease , Aspartic A1
Synonyms: CTSD, CPSD, CLN10, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease, ProCathepsin D, CatD, Cathepsin D
Target Sequences: NM_001909 NP_001900.1 P07339

Publications (2)

1
Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aß and tau pathology. Perez SE, He B, Nadeem M, Wuu J, Ginsberg SD, Ikonomovic MD, Mufson EJ. Journal of neuropathology and experimental neurology. 2015 74:345-58. (WB; Human) [Full Text Article] [PubMed:25756588] [PMC:PMC4366294]
2
Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence. Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper DS. Carcinogenesis. 2015 November;36:1263-1274. [Full Text Article] [PubMed:26354777]

☰ Filters
Products
ELISA Kits (38)
Competitive EIA (3)
Custom (6)
Sandwich (25)
Sandwich CLIA (4)
CTSD / Cathepsin D (38)
Human (11)
Mouse (9)
Rat (6)
Bovine (1)
Chicken (2)
Cow (1)
Dog (1)
Guinea pig (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (6)
96-Well Strip Plate (29)
No (38)
Ascites (1)
Cell Culture Supernatants (6)
Cell Lysates (1)
Plasma (27)
Serum (27)
Tissue Homogenates (9)
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$750
CTSD / Cathepsin D ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
2.74 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$871
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$632
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
46.88 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
23.438 - 1500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
83 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Ascites, Plasma, Serum, Tissue Homogenates
1 Plate/$968
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Cow
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$816
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.049 - 12 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
CTSD / Cathepsin D ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Bovine
2.47 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$816
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CTSD / Cathepsin D ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CTSD / Cathepsin D ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
CTSD / Cathepsin D ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
CTSD / Cathepsin D ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
CTSD / Cathepsin D ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
CTSD / Cathepsin D ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Viewing 1-25 of 38 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).