CTSC / Cathepsin C / JP

cathepsin C

CTSC / Cathepsin C / JP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

CTSC / Cathepsin C / JP (9)

Publications

No (9)

Tag

GST (1)

His (3)

Myc-DDK (Flag) (5)

Species

Human (6)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Mouse CTSC / Cathepsin C / JP Protein (Recombinant His) (aa231-462) - LS-G15102

Source:

E. coli

Tag:

His

Molecular Weight:

27.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human CTSC / Cathepsin C / JP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65424

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.5 kDa

Price:

20 µg/$1,107

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Human CTSC / Cathepsin C / JP Protein (Recombinant His) (Met1-Leu463) - LS-G98520

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51 kDa

Price:

50 µg/$854

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CTSC / Cathepsin C / JP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99578

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.84 kDa

Price:

100 µg/$710

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CTSC / Cathepsin C / JP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106489

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

100 µg/$494

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Human CTSC / Cathepsin C / JP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75535

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.84 kDa

Price:

20 µg/$215

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Human CTSC / Cathepsin C / JP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75536

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

20 µg/$150

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Human CTSC / Cathepsin C / JP Protein (Recombinant GST) (Full Length) - LS-G27902

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CTSC / Cathepsin C / JP Protein (Recombinant His) (aa231-463) - LS-G15099

Source:

E. coli

Tag:

His

Molecular Weight:

27.6 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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