CTSB / Cathepsin B

cathepsin B

Cathepsin B is a lysosomal cysteine proteinase synthesized as a zymogen of 39-47 kilodaltons (kD), which is subsequently converted into an active single- chain form of 33 kD (CB33) and, by additional processing, into the active 2-chain form containing a heavy chain of 27-29 kD (CB(27-29)) and a light chain of 4-6 kD. Cathepsin B is usually found in perinuclear lysosomes of epithelial cells of normal organs and non-malignant tumors, but is associated with the plasma membranes of many solid organ malignant tumors. Cathepsin B, a marker of the dedifferentiated chondrocyte phenotype, has been shown to contribute to cartilage destruction in osteoarthritis and pathological proteolysis in rheumatoid arthritis and cancer. Increased or altered CB expression has been documented in a variety of tumor cells. It has also been suggested that a cat B-mitochondrial apoptotic pathway plays a pivotal role in TNF-alpha-induced hepatocyte apoptosis and liver injury.

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Products

Antibodies (71)

Type

Primary (71)

Target

CTSB / Cathepsin B (71)

Reactivity

Human (51)

Mouse (25)

Rat (20)

Monkey (2)

Application

IHC (21)

IHC-P (14)

WB (58)

Flo (4)

ELISA (28)

ICC (1)

IF (5)

IP (1)

Peptide-ELISA (5)

Host

rabbit (65)

mouse (2)

goat (3)

sheep (1)

Product Group

Antibodies to Coronavirus-Associated Targets (70)

Coronavirus Antibodies Proteins cDNAs (70)

IHCPlus (4)

PathPlus Neuro (3)

Isotype

IgG (30)

IgG1 (1)

Clonality

monoclonal mc (2)

polyclonal pc (69)

Clone

010 (1)

Format

APC (3)

APC Conjugated (5)

Biotin Conjugated (7)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (6)

HRP Conjugated (7)

PE Conjugated (5)

Preservative Free (3)

Unconjugated (35)

Epitope

aa129-333 (24)

aa198-227 (7)

Internal (3)

Internal Region (3)

aa80-333 (2)

Asn217 (1)

aa1-339 (1)

aa168-217 (1)

aa18-339 (1)

aa200-270 (1)

Publications

No (71)

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PathPlus™ CTSB / Cathepsin B Antibody (aa198-227) LS-B9053

Neuroscience

(5.0) Rating

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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PathPlus™ CTSB / Cathepsin B Antibody (Internal Region) LS-B16445

Neuroscience

(5.0) Rating

Antibody:

CTSB / Cathepsin B Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ CTSB / Cathepsin B Antibody (Internal Region) LS-B16436

(4.0) Rating

Antibody:

CTSB / Cathepsin B Goat anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$460

Select

CTSB / Cathepsin B Antibody LS-C660201

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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IHC-plus™ CTSB / Cathepsin B Antibody LS-B16843

(4.0) Rating

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

CTSB / Cathepsin B Antibody (aa200-270) LS-C359263

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa200-270) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

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CTSB / Cathepsin B Antibody (clone 010, Preservative Free) LS-C819219

Antibody:

CTSB / Cathepsin B Rabbit anti-Mouse Monoclonal (Preservative Free) (010) Antibody

Reactivity:

Mouse

Applications:

IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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PathPlus™ CTSB / Cathepsin B Antibody (Internal) LS-B16590

Neuroscience

(5.0) Rating

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

CTSB / Cathepsin B Antibody LS-C211768

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CTSB / Cathepsin B Antibody (HRP) LS-C211770

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CTSB / Cathepsin B Antibody (Biotin) LS-C211774

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

CTSB / Cathepsin B Antibody (FITC) LS-C211773

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CTSB / Cathepsin B Antibody LS-C484012

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

IHC-plus™ CTSB / Cathepsin B Antibody LS-B16740

(4.0) Rating

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

60 µl/$460

Select

CTSB / Cathepsin B Antibody (aa168-217) LS-C291681

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa168-217) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CTSB / Cathepsin B Antibody (aa198-227) LS-C330369

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

CTSB / Cathepsin B Antibody (aa198-227, HRP) LS-C544073

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

CTSB / Cathepsin B Antibody (aa198-227, Biotin) LS-C523948

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

CTSB / Cathepsin B Antibody (aa198-227, PE) LS-C275982

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

CTSB / Cathepsin B Antibody (aa198-227, APC) LS-C275984

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (aa198-227) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • PE
  • APC

Select

CTSB / Cathepsin B Antibody (Internal) LS-C382467

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CTSB / Cathepsin B Antibody LS-C484015

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

IHC-plus™ CTSB / Cathepsin B Antibody LS-B16742

(4.0) Rating

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

60 µl/$460

Select

CTSB / Cathepsin B Antibody (Asn217) LS-C177596

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal (Asn217) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CTSB / Cathepsin B Antibody LS-C417010

Antibody:

CTSB / Cathepsin B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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