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CTPS

CTP synthase 1

This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.

Gene Name: CTP synthase 1
Synonyms: CTPS1, CTP synthase, CTP synthetase 1, CTP synthase 1, CTPS, UTP--ammonia ligase 1
Target Sequences: NM_001905 NP_001896.2 P17812

Publications (1)

1
Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular juvenescence. Takao Morimune , Ayami Tano , Yuya Tanaka , Haruka Yukiue, Takefumi Yamamoto, Ikuo Tooyama, Yoshihiro Maruo, Masaki Nishimura, Masaki Mori. PloS one. 2021 Apr;16:e0248517. [Full Text Article] [PubMed:33886577] [PMC:PMC8062039] Related Antibodies: LS-C197001.

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
CTPS (6)
No (6)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
GST (1)
Myc-DDK (Flag) (3)
Human (4)
Streptococcus pyogenes (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (3)
CTPS Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
1 mg/$1,607; 100 µg/$469; 20 µg/$349
CTPS Protein - Purified recombinant protein CTPS1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
66.5 kDa
20 µg/$1,107
CTPS Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
CTPS Protein - 12.5% SDS-PAGE of human CTPS stained with Coomassie Blue
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Wheat Germ Extract
GST
90.75 kDa
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
66.5 kDa
20 µg/$150
CTPS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
66.5 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).