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This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Gene Name: | CTP synthase 1 |
Synonyms: | CTPS1, CTP synthase, CTP synthetase 1, CTP synthase 1, CTPS, UTP--ammonia ligase 1 |
Target Sequences: | NM_001905 NP_001896.2 P17812 |
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