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CTBP1 / CTBP is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Gene Name: | C-terminal binding protein 1 |
Synonyms: | CTBP1, BARS, C-terminal binding protein 1, C-terminal-binding protein 1, CTBP |
Target Sequences: | NM_001328 NP_001319.1 Q13363 |
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