CSTB / Cystatin B / Stefin B

cystatin B (stefin B)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

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Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

CSTB / Cystatin B / Stefin B (12)

Publications

No (12)

Tag

6His-SUMO, N-terminus (1)

GST (2)

His (5)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Bovine (1)

Human (8)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (7)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

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Bovine CSTB / Cystatin B / Stefin B Protein (Recombinant His) (aa1-98) - LS-G16006

Source:

E. coli

Tag:

His

Molecular Weight:

12.4 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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CSTB / Cystatin B / Stefin B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123387

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11 kDa

Price:

100 µg/$494

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65334

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11 kDa

Price:

20 µg/$1,107

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant 6His-SUMO, N-terminus) - LS-G56191

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CSTB / Cystatin B / Stefin B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75371

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11 kDa

Price:

20 µg/$150

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Mouse CSTB / Cystatin B / Stefin B Protein (Recombinant His) (aa2-98) - LS-G16009

Source:

E. coli

Tag:

His

Molecular Weight:

12.2 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant His-T7) (aa1-98) - LS-G16014

Source:

E. coli

Tag:

His-T7

Molecular Weight:

15.0 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Rat CSTB / Cystatin B / Stefin B Protein (Recombinant His) (aa2-98) - LS-G16015

Source:

E. coli

Tag:

His

Molecular Weight:

12.3 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant GST) (Full Length) - LS-G28081

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.52 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant GST) (Full Length) - LS-G28083

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.52 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant His) - LS-G3381

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human CSTB / Cystatin B / Stefin B Protein (Recombinant His) (Met2-Phe98) - LS-G97356

Source:

E. coli

Tag:

His

Molecular Weight:

12.5 kDa

Price:

100 µg/$721

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