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CST3 / Cystatin C

cystatin C

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.

Gene Name: cystatin C
Synonyms: CST3, ARMD11, BA218C14.4 (cystatin C), Cystatin-3, Cystatin 3, Cystatin C, Cystatin-C, Gamma-trace, Post-gamma-globulin
Target Sequences: NM_000099 NP_000090.1 P01034

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Antibodies (199)
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CST3 / Cystatin C (281)
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CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$515
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Microplate
Canine
10.24 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$760
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Microplate
Human
0.3 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CST3 / Cystatin C Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CST3 / Cystatin C Mouse anti-Human Monoclonal (2C8) Antibody
Human
IHC-P, WB
Unconjugated
50 µl/$460
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
1 Plate/$715
CST3 / Cystatin C ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CST3 / Cystatin C Protein - Recombinant Cystatin 3 By SDS-PAGE
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E. coli
6His, N-terminus
14.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CST3 / Cystatin C Mouse anti-Human Monoclonal (aa95-122) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$525
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CST3 / Cystatin C Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CST3 / Cystatin C Antibody - IHC analysis of Cystatin C using anti-Cystatin C antibody. Cystatin C was detected in paraffin-embedded section of mouse brain tissue . Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2?g/ml rabbit anti-Cystatin C Antibody overnight at 4?C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37?C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CST3 / Cystatin C Antibody - Western blot of Cystatin C antibody
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CST3 / Cystatin C Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CST3 / Cystatin C Rabbit anti-Mouse Monoclonal (Preservative Free) (041) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
CST3 / Cystatin C Antibody - Western blot of recombinant CST3 / Cystatin C.
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CST3 / Cystatin C Rabbit anti-Pig Polyclonal (aa42-127) Antibody
Pig
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
CST3 / Cystatin C Antibody - Western Blot; Sample: Recombinant CST3, Human.
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CST3 / Cystatin C Mouse anti-Human Monoclonal (APC) Antibody
Rat, Human
WB
APC Conjugated
100 µl/$373; 200 µl/$443; 500 µl/$715; 1 ml/$873; 2 ml/$1,124; 5 ml/$2,031
CST3 / Cystatin C Antibody - Immunohistochemistry of paraffin-embedded human prostate.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
1 mg/$429
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CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
1 ml/$248
CST3 / Cystatin C Antibody - Immunohistochemical analysis of human-kidney tissue. Anti-Cystatin C at 1:200 (4°C, overnight). Antigen retrieval - Sodium Citrate pH6 (>98°C, 20min). Secondary - 1:200 (room temp, 30min). Negative control - Secondary only
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CST3 / Cystatin C Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CST3 / Cystatin C Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal (3B6) Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 281 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).