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CSRNP1 / AXUD1 is a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function.
Gene Name: | cysteine-serine-rich nuclear protein 1 |
Synonyms: | CSRNP1, AXUD1, CSRNP-1, FAM130B, Protein URAX1, TAIP3, AXIN1 up-regulated 1, TAIP-3, URAX1 |
Target Sequences: | NM_033027 NP_149016.2 Q96S65 |
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