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CSNK2B / Phosvitin is the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | casein kinase 2, beta polypeptide |
Family/Subfamily: | Protein Kinase Non Catalytic , Casein kinase II |
Synonyms: | CSNK2B, CK2N, Casein kinase 2 beta, Casein kinase II beta, CK II beta, CSK2B, G5A, Protein G5a, Casein kinase II beta subunit, Casein kinase II subunit beta, CK2B, Phosvitin |
Target Sequences: | NM_001320 NP_001311.3 P67870 |
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