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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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CSNK1G2 / CKI-Gamma 2
casein kinase 1, gamma 2
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
| Gene Name: | casein kinase 1, gamma 2 |
| Family/Subfamily: | Protein Kinase , Casein kinase I |
| Synonyms: | CSNK1G2, Casein kinase 1, gamma 2, Casein kinase I gamma 2, CKI Gamma 2, CKI-gamma 2, CK1 gamma 2, CK1g2, Casein Kinase 1 gamma 2 |
| Target Sequences: | NM_001319 NP_001310.3 P78368 |
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Antibodies
(57)
Proteins
(8)
ELISA Kits
(1)
Type
Cell-Based
(1)
Over-Expression Lysate
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Primary
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Recombinant
(6)
Target
CSNK1G2 / CKI-Gamma 2
(66)
Reactivity
Human
(58)
Mouse
(24)
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(11)
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(4)
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(6)
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(55)
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rabbit
(32)
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monoclonal mc
(25)
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(32)
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(3)
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(1)
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(5)
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(9)
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(5)
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(3)
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(36)
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aa163-415
(18)
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(7)
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(4)
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(1)
Gly7
(1)
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(1)
aa10-59
(1)
aa315-415
(1)
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No
(66)
Sample Type
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(1)
Tag
6His, N-terminus
(2)
GST
(1)
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(1)
GST, N-terminus + His, C-terminus
(1)
His
(1)
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(2)
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(8)
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293T Cells
(1)
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(1)
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(3)
HEK 293 Cells
(1)
Wheat Germ Extract
(2)
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Purified
(2)
Low Endotoxin Level
Low endotoxin level
(3)
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa163-415) (OTI4H3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa163-415) (Carrier-free) (OTI4H3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HEK 293 Cells
Myc-DDK (Flag)
47.3 kDa
100 µg/$494
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (Gly7) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa315-415) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (3F4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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product results
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