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CSF2RA / CD116 is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
Gene Name: | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
Synonyms: | CSF2RA, CD116, CD116 antigen, CDw116, CSF2R, CSF2RX, CSF2RY, CSF2RAY, GM-CSF-R-alpha, GM-CSF receptor alpha subunit, GMCSFR, GMR, GMR-alpha, SMDP4, CSF2RAX, GMCSFR-alpha, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha |
Target Sequences: | NP_006131.2 P15509 |
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