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CSF2 / GM-CSF
colony stimulating factor 2 (granulocyte-macrophage)
CSF2 / GM-CSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
| Gene Name: | colony stimulating factor 2 (granulocyte-macrophage) |
| Synonyms: | CSF2, Colony-stimulating factor, CSF, GM-CSF, Molgramostin, GMCSF |
| Target Sequences: | NM_000758 NP_000749.2 P04141 |
Publications (2)
1
Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer. Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S. Cancer research. 2015 75:2629-40. (IHC; Human)
[Full Text Article]
[PubMed:25952647]
Related Antibodies: LS-C104671.
2
Expression of granulocyte macrophage-colony stimulating factor and its receptor in the synovium of osteoarthritis patients is negatively correlated with pain. Eefje M van Helvoort, Niels Eijkelkamp, Floris P J G Lafeber, Simon C Mastbergen. Rheumatology (Oxford, England). 2020 November;59:3452-3457. [Full Text Article]
[PubMed:32365364]
☰ Filters
Products
Proteins
(58)
Type
Over-Expression Lysate
(2)
Recombinant
(55)
Target
CSF2 / GM-CSF
(58)
Format
Animal-free
(3)
Publications
No
(58)
Tag
6His, C-terminus
(8)
6His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(2)
His, N-Terminal
(1)
His, N-terminus
(1)
His,C-terminus
(1)
His-GST
(2)
His-GST, N-terminus
(2)
Myc-DDK (Flag)
(3)
Species
Bovine
(1)
Human
(32)
Monkey-Rhesus
(1)
Mouse
(14)
Rat
(7)
Rhesus monkey
(1)
Source
293F Cells
(1)
293T Cells
(1)
CHO Cells
(3)
E. coli
(32)
HEK 293 Cells
(4)
Human
(1)
Human Cells
(3)
Human Embryonic Kidney 293 Cells
(1)
Mammalian Cells
(5)
Pichia pastoris
(1)
Wheat Germ Extract
(1)
Yeast
(3)
Purification
Purified
(23)
Low Endotoxin Level
Low endotoxin level
(37)
Biologically Active
Biologically active
(27)
Animal-free
Animal-free
(3)
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
15~19 kDa (SDS-PAGE)
50 µg/$478; 10 µg/$296; 1 mg/$2,653
HEK 293 Cells
His
16.1 kDa
10 µg/$352; 50 µg/$702; 100 µg/$1,042
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
14.5 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$282; 20 µg/$370
E. coli
His-GST
46.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
14.6 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$281; 20 µg/$369
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
14.2 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$281; 20 µg/$369
E. coli
None
100 µg/$479; 500 µg/$1,243; 20 µg/$329; 10 µg/$279; 50 µg/$373; 250 µg/$769
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$511; 500 µg/$1,355; 20 µg/$323; 10 µg/$286; 50 µg/$392; 250 µg/$872
E. coli
None
Biologically active
14.5 kDa
5 µg/$282; 100 µg/$1,030; 500 µg/$1,891
E. coli
None
Biologically active
14.1 kDa
5 µg/$282; 100 µg/$1,030; 500 µg/$1,891
E. coli
None
Biologically active
14.4 kDa
10 µg/$388; 100 µg/$1,186; 500 µg/$2,269
E. coli
His-GST, N-terminus
41.5 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Yeast
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.4kD
10 µg/$288; 50 µg/$442; 500 µg/$1,484; 1 mg/$1,961
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.2kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.6kD
10 µg/$277; 50 µg/$395; 500 µg/$1,262; 1 mg/$1,627
Human
None
50 µg/$542; 10 µg/$297; 200 µg/$1,065; 100 µg/$865; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
HEK 293 Cells
Myc-DDK (Flag)
14.4 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
16.29 kDa
100 µg/$494
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.6kD
10 µg/$297; 50 µg/$468; 500 µg/$1,353; 1 mg/$1,725
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of 58
product results
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