CRYBB2

crystallin, beta B2

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts.

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Products

ELISA Kits (6)

Type

Development Kit (3)

Sandwich (3)

Target

CRYBB2 (6)

Reactivity

Human (2)

Mouse (2)

Rat (2)

Product Group

DevKit DuoPlus (3)

Format

96-Well Strip Plate (3)

Antibody Pair and Standard (3)

Publications

No (6)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (6)

Plasma (1)

Serum (1)

Tissue Homogenates (6)

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Mouse CRYBB2 (Sandwich ELISA) ELISA Kit - LS-F25489

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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DevKit DuoPlus Mouse CRYBB2 ELISA Development Kit - LS-F72090

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,302; 1000 Wells/$1,947

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DevKit DuoPlus Human CRYBB2 ELISA Development Kit - LS-F71549

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,178; 1000 Wells/$1,739

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DevKit DuoPlus Rat CRYBB2 ELISA Development Kit - LS-F71646

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,186; 1000 Wells/$1,754

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Rat CRYBB2 (Sandwich ELISA) ELISA Kit - LS-F55345

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Human CRYBB2 (Sandwich ELISA) ELISA Kit - LS-F55034

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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