CRTC2 / TORC2

CREB regulated transcription coactivator 2

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CRTC2 / TORC2 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CRTC2 / TORC2 Protein (Recombinant GST) (Full Length) - LS-G36948

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

99.7 kDa

Price:

2 µg/$439

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Human CRTC2 / TORC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93804

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.1 kDa

Price:

20 µg/$150

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Human CRTC2 / TORC2 Protein (Recombinant GST, N-terminus) (aa595-693) - LS-G63804

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CRTC2 / TORC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102509

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.1 kDa

Price:

100 µg/$494

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