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CRTAP is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
Gene Name: | cartilage associated protein |
Synonyms: | CRTAP, CASP, Cartilage-associated protein, LEPREL3, Leprecan-like 3, OI7, Cartilage associated protein |
Target Sequences: | AK001634 |
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