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CRLF2 / TSLPR

cytokine receptor-like factor 2

CRLF2 / TSLPR is a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Gene Name: cytokine receptor-like factor 2
Synonyms: CRLF2, IL-XR, ILXR, p2RY8/CRLF2 fusion, TSLP receptor, TSLPR, CRL2, CRLF2Y, Cytokine receptor-like 2
Target Sequences: AK026800 BAB15557.1 Q9HC73

Publications (1)

1
Anti-CRLF2 Antibody-Armored Biodegradable Nanoparticles for Childhood B-ALL. Raghunathan R, Mahesula S, Kancharla K, Janardhanan P, Jadhav YL, Nadeau R, Villa GP, Cook RL, Witt CM, Gelfond JA, Forsthuber TG, Haskins WE. Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems. 2013 30:355-364. (WB; Human) [Full Text Article] [PubMed:23976822] [PMC:PMC3746557] Related Antibodies: LS-C40791.

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Antibodies (31)
Primary (31)
CRLF2 / TSLPR (31)
Human (29)
Mouse (4)
Rat (2)
Gibbon (3)
IHC (7)
IHC-P (4)
WB (26)
Flo (2)
ELISA (17)
IF (2)
IHC-Fx (1)
rabbit (18)
mouse (12)
goat (1)
Product Group
IHCPlus (1)
IgG (12)
IgG1 (2)
IgG1,k (1)
IgG2a,k (7)
IgG2b,k (1)
monoclonal mc (12)
polyclonal pc (19)
1B4 (1)
59N5G4 (1)
8H8 (2)
AT4E7 (1)
APC Conjugated (1)
Biotin Conjugated (3)
CF Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (18)
aa71-120 (4)
aa119-231 (1)
aa23-133 (1)
No (30)
Yes (1)
CRLF2 / TSLPR Antibody - Anti-CRLF2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CRLF2 / TSLPR Antibody - Human monocyte-derived dendritic cells stained with purified 1B4, followed by biotinylated anti-mouse IgG and Sav-PE
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (1B4) Antibody
Human
Flo, WB
Unconjugated
100 µg/$352
CRLF2 / TSLPR Antibody - Immunohistochemistry-Paraffin: TSLP R/CRLF2 Antibody (59N5G4) - Formalin-fixed, paraffin-embedded normal human kidney tissue stained with TSLPR antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (aa119-231) (59N5G4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
CRLF2 / TSLPR Antibody - Staining of mouse splenocytes using Thymic Stromal Lymphopoietin Protein Receptor (TSLP R) (Carboxyfluorescein) (CFS) (filled histogram) or isotype control (open histogram). This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Goat anti-Mouse Polyclonal (CF) Antibody
Mouse
Flo
CF Conjugated
100 Tests/$755
CRLF2 / TSLPR Antibody - Immunofluorescence of TSLP Receptor in Mouse Liver cells with TSLP Receptor antibody at 20 ug/ml.
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CRLF2 / TSLPR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IF, WB
Unconjugated
0.1 mg/$460
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (8H8) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$468
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
CRLF2 / TSLPR Antibody - Staining of human thymus with Cytokine Receptor-like Factor 2 Monoclonal Antibody
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (8H8) Antibody
Human
ELISA, IHC-Fx, IHC-P, WB
Unconjugated
100 µg/$575
CRLF2 / TSLPR Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CRLF2 / TSLPR Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using CRLF2 Polyclonal Antibody at dilution of 1:60.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CRLF2 / TSLPR Antibody - Immunohistochemistry of paraffin-embedded human liver tissue anti-CRLF2 antibody at dilution 1:100
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$391
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (aa23-133) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
CRLF2 / TSLPR Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using CRLF2 Polyclonal Antibody at dilution of 1:60.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CRLF2 / TSLPR Antibody - Western Blot: The cell lysate of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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CRLF2 / TSLPR Mouse anti-Human Monoclonal (AT4E7) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
CRLF2 / TSLPR Antibody - Western blot - Anti-CRLF2/Tslp R Picoband antibody
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
CRLF2 / TSLPR Antibody - Fig-1: Western blot analysis of TSLPR. Anti-TSLPR antibody was used at 2 µg/ml on human heart lysate.
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CRLF2 / TSLPR Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
25 µg/$288; 100 µg/$414
CRLF2 / TSLPR Antibody - CRLF2 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
CRLF2 / TSLPR Antibody - CRLF2 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Human, Gibbon
WB
HRP Conjugated
100 µl/$469
CRLF2 / TSLPR Antibody - CRLF2 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Human, Gibbon
WB
Biotin Conjugated
100 µl/$469
CRLF2 / TSLPR Antibody - CRLF2 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRLF2 / TSLPR Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Human, Gibbon
WB
FITC Conjugated
100 µl/$469
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).