CRF2-12 / IL28RA

interferon, lambda receptor 1

The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CRF2-12 / IL28RA (4)

Publications

No (4)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CRF2-12 / IL28RA Protein (Recombinant) (aa21-228) - LS-G64229

Source:

E. coli

Tag:

None

Price:

1 mg/$1,568; 100 µg/$534; 20 µg/$422

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Human CRF2-12 / IL28RA Protein (Recombinant GST, N-terminus) (aa51-150) - LS-G64690

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

25 µg/$670; 10 µg/$479

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Human CRF2-12 / IL28RA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84597

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.2 kDa

Price:

20 µg/$215

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CRF2-12 / IL28RA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105400

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.2 kDa

Price:

100 µg/$710

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