CREBL2

cAMP responsive element binding protein-like 2

cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CREBL2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CREBL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82572

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

13.6 kDa

Price:

20 µg/$150

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Human CREBL2 Protein (Recombinant GST, N-terminus) (aa31-120) - LS-G58210

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CREBL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118669

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

13.6 kDa

Price:

100 µg/$494

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Human CREBL2 Protein (Recombinant His, N-Terminal) - LS-G144518

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

13.6 kDa

Price:

50 µg/$419

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Human CREBL2 Protein (Recombinant GST) (Full Length) - LS-G28018

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

40.2 kDa

Price:

10 µg/$479; 25 µg/$670

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