CREBBP / CREB Binding Protein

CREB binding protein

CREBBP / CREB Binding Protein is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

CREBBP / CREB Binding Protein (7)

Publications

No (7)

Tag

GST, N-terminus (1)

His (4)

Myc-DDK (Flag) (2)

Species

Human (3)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Sf21 Cells (1)

Wheat Germ Extract (1)

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Human CREBBP / CREB Binding Protein (Recombinant His) (aa2141-2442) - LS-G15417

Source:

E. coli

Tag:

His

Molecular Weight:

33.8 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Rat CREBBP / CREB Binding Protein (Recombinant His) (aa2216-2442) - LS-G15426

Source:

E. coli

Tag:

His

Molecular Weight:

25.4 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human CREBBP / CREB Binding Protein (Recombinant GST, N-terminus) (aa951-1050) - LS-G58208

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CREBBP / CREB Binding Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75325

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

265.2 kDa

Price:

20 µg/$215

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CREBBP / CREB Binding Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116692

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

265.2 kDa

Price:

100 µg/$710

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Mouse CREBBP / CREB Binding Protein (Recombinant His) - LS-G3992

Source:

Sf21 Cells

Tag:

His

Price:

2 µg/$365

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Mouse CREBBP / CREB Binding Protein (Recombinant His) (aa2215-2441) - LS-G15423

Source:

E. coli

Tag:

His

Molecular Weight:

25.4 kDa

Price:

10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136

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