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CRADD / RAIDD

CASP2 and RIPK1 domain containing adaptor with death domain

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD). RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.

Gene Name: CASP2 and RIPK1 domain containing adaptor with death domain
Family/Subfamily: Apoptosis , Not assigned-Other
Synonyms: CRADD, Death adaptor molecule RAIDD, RAIDD, MRT34
Target Sequences: NM_003805 NP_003796.1 P78560

Publications (1)

1
Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance. Irmina Garcia-Carpio, Vincent Z Braun, Elias S Weiler, Marina Leone, Sergio Niñerola, Angel Barco, Luca L Fava, Andreas Villunger. The EMBO journal. 2023 October;42:e113510. [Full Text Article] [PubMed:37530438] [PMC:PMC10398658] Related Antibodies: LS-C179788.

☰ Filters
Antibodies (58)
Proteins (11)
Over-Expression Lysate (2)
Primary (58)
Recombinant (9)
CRADD / RAIDD (69)
Human (58)
Mouse (7)
Rat (7)
IHC (13)
IHC-P (8)
WB (56)
Flo (1)
ELISA (24)
ICC (7)
IF (8)
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rabbit (39)
mouse (18)
goat (1)
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IgG (31)
IgG1 (1)
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monoclonal mc (19)
polyclonal pc (39)
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AT14G8 (1)
EPR1640Y (1)
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APC Conjugated (4)
Azide-free (1)
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Cy3 Conjugated (2)
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CRADD / RAIDD Antibody
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (4B12) Antibody
Human
WB
Unconjugated
100 µg/$425
CRADD / RAIDD Antibody - Anti-CRADD / RAIDD antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CRADD / RAIDD Antibody - IHC of paraffin-embedded human heart muscle using anti-RAIDD antibody.
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CRADD / RAIDD Rabbit anti-Human Monoclonal (C-Terminus) (EPR1640Y) Antibody
Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$478
CRADD / RAIDD Antibody - Immunohistochemistry of RAIDD in human kidney tissue with RAIDD antibody at 10 µg/ml.
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CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
CRADD / RAIDD Antibody - Anti-CRADD rabbit polyclonal antibody at 1:500 dilution. Lane A: K562 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 23 kDa. Observed band size: 23 kDa. (We are unsure as to the identity of these extra bands.)
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CRADD / RAIDD Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
CRADD / RAIDD Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRADD / RAIDD Rabbit anti-Human Polyclonal (aa1-199) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CRADD / RAIDD Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRADD / RAIDD Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CRADD / RAIDD Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRADD / RAIDD Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CRADD / RAIDD Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CRADD / RAIDD Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Select
CRADD / RAIDD Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
CRADD / RAIDD Antibody - ICC/IF analysis of CRADD in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CRADD antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of CRADD in PC3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CRADD antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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CRADD / RAIDD Mouse anti-Human Monoclonal (AT14G8) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
CRADD / RAIDD Antibody - Immunohistochemistry of paraffin-embedded human rectum tissue using antibody at 1:100 dilution.
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CRADD / RAIDD Rabbit anti-Human Polyclonal (aa1-199) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CRADD / RAIDD Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CRADD / RAIDD Antibody - Western blot of CRADD pAb in extracts from K562 cells.
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CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CRADD / RAIDD Antibody - Western blot analysis of K562 cell lysate.
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CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CRADD / RAIDD Antibody - Immunohistochemical staining of RAIDD in human kidney with RAIDD antibody at 10µg/ml.
Select
CRADD / RAIDD Rabbit anti-Human Polyclonal (aa181-199) Antibody
Human
IHC, WB
Unconjugated
100 µg/$522
Select
CRADD / RAIDD Rabbit anti-Human Polyclonal (aa69-98) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (aa1-199) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
200 µl/$389
Select
CRADD / RAIDD Mouse anti-Human Monoclonal (aa1-199) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
200 µl/$405
Select
CRADD / RAIDD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 69 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).