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Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Gene Name: | cleavage and polyadenylation specific factor 2, 100kDa |
Synonyms: | CPSF2, CPSF 100kDa subunit, CPSF100, CPSF 100 kDa subunit, KIAA1367 |
Target Sequences: | AB037788 BAA92605.1 Q9P2I0 |
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