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Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.
Gene Name: | carboxypeptidase B1 (tissue) |
Family/Subfamily: | Exopeptidase , Metallopeptidase M14 |
Synonyms: | CPB1, Carboxypeptidase B, Carboxypeptidase B1 (tissue), CPB, Pancreatic carboxypeptidase B, PASP, Procarboxypeptidase B, Protaminase, Pancreas-specific protein, PCPB, Tissue carboxypeptidase B |
Target Sequences: | NM_001871 NP_001862.2 P15086 |
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