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CPA3

carboxypeptidase A3 (mast cell)

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A3 form, is obtained as a binary complex of a procarboxypeptidase A with a proproteinase E. Mast cell carboxypeptidase A is a secretory granule metalloexopeptidase that has a pH optimum in the neutral to basic range. It resembles pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues.

Gene Name: carboxypeptidase A3 (mast cell)
Family/Subfamily: Exopeptidase , Metallopeptidase M14
Synonyms: CPA3, Carboxypeptidase A3, Mast cell carboxypeptidase A, MC-CPA, Tissue carboxypeptidase A
Target Sequences: NM_001870 NP_001861.2 P15088

Publications (2)

1
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody. Simon Gebremeskel, Julia Schanin, Krysta M Coyle, Melina Butuci, Thuy Luu, Emily C Brock, Alan Xu, Alan Wong, John Leung, Wouter Korver, Ryan D Morin, Robert P Schleimer, Bruce S Bochner, Bradford A Youngblood. Frontiers in immunology. 2021 March;12:650331. [Full Text Article] [PubMed:33777047] [PMC:PMC7988091]
2
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation. Olga Krysko, Joshua H Bourne, Elena Kondakova, Elena A Galova, Katharine Whitworth, Maddy L Newby, Claus Bachert, Harriet Hill, Max Crispin, Zania Stamataki, Adam F Cunningham, Matthew Pugh, Abdullah O Khan, Julie Rayes, Maria Vedunova, Dmitri V Krysko, Alexander Brill. Frontiers in immunology. 2022 October;13:968981. [Full Text Article] [PubMed:36225927] [PMC:PMC9548604]

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Products
Antibodies (30)
Primary (30)
CPA3 (30)
Human (21)
Mouse (21)
Rat (17)
Bovine (3)
Dog (3)
Gibbon (3)
Monkey (3)
IHC (1)
WB (29)
Flo (7)
ELISA (8)
Peptide-ELISA (1)
rabbit (29)
mouse (1)
IgG (7)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (29)
2D1 (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (8)
aa110-417 (8)
aa16-417 (8)
aa255-284 (7)
aa91-140 (4)
No (30)
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (HRP) Antibody
Mouse, Rat
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (FITC) Antibody
Mouse, Rat
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (APC) Antibody
Mouse, Rat
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (APC, Cy7) Antibody
Mouse, Rat
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (PE) Antibody
Mouse, Rat
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
CPA3 Antibody - Western blot of CPA3 antibody.
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CPA3 Rabbit anti-Mouse Polyclonal (aa16-417) (Cy3) Antibody
Mouse, Rat
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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CPA3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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CPA3 Rabbit anti-Human Polyclonal (aa255-284) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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CPA3 Rabbit anti-Human Polyclonal (aa255-284) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
CPA3 Rabbit anti-Human Polyclonal (aa255-284) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
CPA3 Rabbit anti-Human Polyclonal (aa255-284) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
CPA3 Rabbit anti-Human Polyclonal (aa255-284) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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CPA3 Rabbit anti-Human Polyclonal (aa255-284) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
CPA3 Antibody - CPA3 Antibody western blot of K562 cell line lysates (35 ug/lane). The CPA3 antibody detected the CPA3 protein (arrow).
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CPA3 Rabbit anti-Human Polyclonal (aa255-284) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
CPA3 Antibody - The Carboxypeptidase A3 Antibody is used in Western blot to detect Carboxypeptidase A3 in HL60 cell lysate.
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CPA3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
0.1 mg/$394
CPA3 Antibody - Detection limit for recombinant GST tagged CPA3 is 3 ng/ml as a capture antibody.
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CPA3 Mouse anti-Human Monoclonal (2D1) Antibody
Human
ELISA
Unconjugated
100 µg/$423
CPA3 Antibody - CPA3 antibody Western blot of Mouse Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPA3 Rabbit anti-Mouse Polyclonal (aa91-140) Antibody
Mouse
WB
Unconjugated
100 µl/$424
CPA3 Antibody - CPA3 antibody Western blot of Mouse Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPA3 Rabbit anti-Mouse Polyclonal (aa91-140) (HRP) Antibody
Mouse, Dog, Bovine, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
CPA3 Antibody - CPA3 antibody Western blot of Mouse Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPA3 Rabbit anti-Mouse Polyclonal (aa91-140) (Biotin) Antibody
Mouse, Dog, Bovine, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$469
CPA3 Antibody - CPA3 antibody Western blot of Mouse Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CPA3 Rabbit anti-Mouse Polyclonal (aa91-140) (FITC) Antibody
Mouse, Dog, Bovine, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$469
CPA3 Antibody - Western blot of recombinant CPA3.
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CPA3 Rabbit anti-Human Polyclonal (aa110-417) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CPA3 Antibody - Western blot of recombinant CPA3.
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CPA3 Rabbit anti-Human Polyclonal (aa110-417) (HRP) Antibody
Mouse, Rat, Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
CPA3 Antibody - Western blot of recombinant CPA3.
Select
CPA3 Rabbit anti-Human Polyclonal (aa110-417) (APC) Antibody
Mouse, Rat, Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).