COX17

COX17 cytochrome c oxidase copper chaperone

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.

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Proteins (2)

Type

Recombinant (2)

Target

COX17 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human COX17 Protein (Recombinant GST) (Full Length) - LS-G31927

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

33.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human COX17 Protein (Recombinant GST, N-terminus) (aa1-63) - LS-G61352

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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