COQ6

coenzyme Q6 monooxygenase

The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

COQ6 (7)

Publications

No (7)

Tag

GST (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (4)

Rat (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Rat COQ6 Protein (Recombinant His-T7) (aa1-476) - LS-G26287

Source:

E. coli

Tag:

His-T7

Molecular Weight:

55.2 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human COQ6 Protein (Recombinant His-T7) (aa1-468) - LS-G26286

Source:

E. coli

Tag:

His-T7

Molecular Weight:

54.6 kDa

Price:

10 µg/$259; 50 µg/$331; 200 µg/$602; 100 µg/$482; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human COQ6 Protein (Recombinant GST) (Full Length) - LS-G33577

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.22 kDa

Price:

2 µg/$439

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Human COQ6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90184

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.7 kDa

Price:

20 µg/$150

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Human COQ6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90186

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43 kDa

Price:

20 µg/$150

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COQ6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104302

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43 kDa

Price:

100 µg/$494

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COQ6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104301

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.7 kDa

Price:

100 µg/$494

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