COPS4 / CSN4

COP9 signalosome subunit 4

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

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Products

Antibodies (13)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (13)

Recombinant (1)

Target

COPS4 / CSN4 (16)

Reactivity

Human (12)

Mouse (9)

Rat (9)

Bat (6)

Bovine (6)

Chicken (3)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Guinea pig (6)

Hamster (6)

Horse (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (2)

IHC-P (1)

WB (13)

ELISA (2)

IP (1)

Peptide-ELISA (1)

Host

rabbit (13)

Isotype

IgG (9)

Clonality

polyclonal pc (13)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (7)

Epitope

aa143-192 (4)

aa53-102 (4)

aa1-310 (1)

aa350-C-term (1)

Publications

No (16)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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COPS4 / CSN4 Antibody (aa350-C-term) LS-C286956

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa350-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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COPS4 / CSN4 Antibody (aa1-310) LS-C379797

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa1-310) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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COPS4 / CSN4 Antibody (aa53-102) LS-C145812

Antibody:

COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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COPS4 / CSN4 Antibody (aa53-102, HRP) LS-C462507

Antibody:

COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

COPS4 / CSN4 Antibody (aa53-102, Biotin) LS-C462506

Antibody:

COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

COPS4 / CSN4 Antibody (aa53-102, FITC) LS-C462505

Antibody:

COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

COPS4 / CSN4 Antibody LS-C664711

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

COPS4 / CSN4 Antibody LS-C803921

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

COPS4 / CSN4 Antibody LS-C409750

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

COPS4 / CSN4 Antibody (aa143-192) LS-C102717

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

COPS4 / CSN4 Antibody (aa143-192, HRP) LS-C462510

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

COPS4 / CSN4 Antibody (aa143-192, Biotin) LS-C462508

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

COPS4 / CSN4 Antibody (aa143-192, FITC) LS-C462509

Antibody:

COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human COPS4 / CSN4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70021

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.1 kDa

Price:

20 µg/$1,107

Select

COPS4 / CSN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101392

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.1 kDa

Price:

100 µg/$494

Select

Human COPS4 / CSN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86093

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.1 kDa

Price:

20 µg/$150

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