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Complement C8g belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Gene Name: | complement component 8, gamma polypeptide |
Synonyms: | C8G, C8C, Complement C8G |
Target Sequences: | NM_000606 NP_000597.2 P07360 |
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