Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Complement C8b is one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.
Gene Name: | complement component 8, beta polypeptide |
Synonyms: | C8B, Complement C8B |
Target Sequences: | NM_000066 NP_000057.2 P07358 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.