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Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself.
Gene Name: | complement component 8, alpha polypeptide |
Synonyms: | C8A, Complement C8A |
Target Sequences: | NM_000562 NP_000553.1 P07357 |
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