Complement C5

complement component 5

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes (PubMed:8182049). C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

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Products

Antibodies (52)

Type

Primary (51)

Secondary (1)

Target

Complement C5 (52)

Reactivity

Human (39)

Mouse (14)

Rat (5)

Application

IHC (13)

IHC-Fr (1)

IHC-P (7)

WB (44)

Flo (1)

ELISA (21)

ID (2)

Neut (1)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (25)

goat (3)

sheep (1)

Product Group

IHCPlus (2)

Isotype

IgG (15)

IgG1 (6)

IgG2a (3)

IgG2a,k (8)

IgG2b,k (8)

Clonality

monoclonal mc (25)

polyclonal pc (27)

Clone

046-10.2.2 (10-04) (1)

2942 (1)

557 (1)

561 (1)

HCC5.1 (1)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (23)

Epitope

aa253-281 (7)

aa678-751 (4)

N-Terminus (2)

aa1-18 (1)

aa1-77 (1)

aa1223-1451 (1)

aa59-77 (1)

Publications

No (52)

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Complement C5 Antibody (aa1-18) LS-C313394

Antibody:

Complement C5 Rabbit anti-Rat Polyclonal (aa1-18) Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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Complement C5 Antibody (aa1-77) LS-C344039

Antibody:

Complement C5 Rabbit anti-Rat Polyclonal (aa1-77) Antibody

Reactivity:

Rat

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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Complement C5 Antibody (clone 557) LS-C14521

Antibody:

Complement C5 Mouse anti-Human Monoclonal (557) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$752

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Complement C5 Antibody LS-C22314

Antibody:

Complement C5 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$862

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Complement C5 Antibody (aa253-281) LS-C168151

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa253-281) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Complement C5 Antibody LS-B15694

Antibody:

Complement C5 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ Complement C5 Antibody LS-B15730

(4.0) Rating

Antibody:

Complement C5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Complement C5 Antibody (HRP) LS-C375365

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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Complement C5 Antibody (aa678-751, Biotin) LS-C375366

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa678-751) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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Complement C5 Antibody (FITC) LS-C375368

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Complement C5 Antibody (clone HCC5.1) LS-C22315

Antibody:

Complement C5 Mouse anti-Human Monoclonal (HCC5.1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

50 µg/$891

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Complement C5 Antibody (clone 2942) LS-C22319

Antibody:

Complement C5 Mouse anti-Human Monoclonal (2942) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$826

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Complement C5 Antibody (N-Terminus, clone 046-10.2.2 (10-04)) LS-C44979

Antibody:

Complement C5 Mouse anti-Human Monoclonal (N-Terminus) (046-10.2.2 (10-04)) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$536

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Complement C5 Antibody LS-C409639

Antibody:

Complement C5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Complement C5 Antibody (aa1223-1451) LS-C186223

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa1223-1451) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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Complement C5 Antibody (N-Terminus, clone 561) LS-C14520

Antibody:

Complement C5 Mouse anti-Human Monoclonal (N-Terminus) (561) Antibody

Reactivity:

Human

Applications:

ELISA, Neut

Format:

Unconjugated

Price:

100 µg/$752

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Complement C5 Antibody LS-C809743

Antibody:

Complement C5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Complement C5 Antibody LS-C140221

Antibody:

Complement C5 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$589

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Complement C5 Antibody LS-C779325

Antibody:

Complement C5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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Complement C5 Antibody LS-C147222

Antibody:

Complement C5 Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID

Format:

Unconjugated

Price:

1 ml/$351

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Complement C5 Antibody (FITC) LS-C147223

Antibody:

Complement C5 Goat anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

IHC

Format:

FITC Conjugated

Price:

1 ml/$438

• Unconjugated
• FITC

• Unconjugated
• FITC

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Complement C5 Antibody (aa59-77) LS-C343934

Antibody:

Complement C5 Rabbit anti-Rat Polyclonal (aa59-77) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$431

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Complement C5 Antibody (aa253-281) LS-C327098

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa253-281) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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Complement C5 Antibody (aa253-281, Biotin) LS-C206463

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa253-281) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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Complement C5 Antibody (aa253-281, Azide-free, HRP) LS-C207952

Antibody:

Complement C5 Rabbit anti-Human Polyclonal (aa253-281) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• HRP, Azide-free

• Unconjugated
• Biotin
• HRP, Azide-free

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