Complement C4b

complement component 4B (Chido blood group)

Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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Products

Proteins (6)

Type

Recombinant (6)

Target

Complement C4b (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST, N-terminus (2)

His (1)

His, N-Terminal (1)

His-SUMO (1)

Species

Human (5)

Mouse (1)

Source

E. coli (3)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (1)

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Human Complement C4b Protein (Recombinant 6His, N-terminus) (aa1454-1744) - LS-G23217

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

35.1 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human Complement C4b Protein (Recombinant His, N-Terminal) (aa680-756) - LS-G13620

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

12.6 kDa

Price:

50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse Complement C4b Protein (Recombinant His) (aa678-753) - LS-G13621

Source:

E. coli

Tag:

His

Molecular Weight:

10.2 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human Complement C4b Protein (Recombinant GST, N-terminus) (aa1347-1446) - LS-G57939

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human Complement C4b Protein (Recombinant His-SUMO) (aa1454-1744) - LS-G21376

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

49.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human Complement C4b Protein (Recombinant GST, N-terminus) (aa774-873) - LS-G57940

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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