Complement C4b

complement component 4B (Chido blood group)

Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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Products

ELISA Kits (15)

Type

Competitive EIA (1)

Custom (1)

Sandwich (12)

Sandwich CLIA (1)

Target

Complement C4b (15)

Reactivity

Human (7)

Mouse (4)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (13)

Publications

No (14)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (11)

Serum (11)

Tissue Homogenates (3)

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Mouse Complement C4b (Sandwich ELISA) ELISA Kit - LS-F8056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Monkey Complement C4b (Sandwich ELISA) ELISA Kit - LS-F42671

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

4.69 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F22486

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

4.688 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$549

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F51574

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$958

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F4550

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F11162

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F33595

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

4.688 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse Complement C4b (Sandwich ELISA) ELISA Kit - LS-F52940

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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Mouse Complement C4b (Custom ELISA) ELISA Kit - LS-F16102

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human Complement C4b (CLIA) ELISA Kit - LS-F29589

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.938 - 60 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Porcine Complement C4b (Sandwich ELISA) ELISA Kit - LS-F42670

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

4.688 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit Complement C4b (Sandwich ELISA) ELISA Kit - LS-F42672

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.188 - 12 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Chicken Complement C4b (Sandwich ELISA) ELISA Kit - LS-F42669

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.234 - 15 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F26755

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

10 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Mouse Complement C4b (Competitive EIA) ELISA Kit - LS-F28258

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

50 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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