Complement C4b

complement component 4B (Chido blood group)

Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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Products

Antibodies (42)

ELISA Kits (15)

Proteins (6)

Type

Competitive EIA (1)

Custom (1)

Primary (42)

Recombinant (6)

Sandwich (12)

Sandwich CLIA (1)

Target

Complement C4b (63)

Reactivity

Human (35)

Mouse (21)

Chicken (1)

Horse (3)

Monkey (4)

Orangutan (3)

Porcine (1)

Rabbit (1)

Application

IHC (6)

IHC-P (6)

WB (30)

Flo (1)

ELISA (12)

Host

rabbit (38)

mouse (3)

chicken (1)

Product Group

IHCPlus (2)

Isotype

IgG (10)

IgG2a (2)

IgG2b,k (1)

IgY (1)

Clonality

monoclonal mc (3)

polyclonal pc (39)

Clone

2E3 (1)

OTI1B2 (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (13)

APC (3)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (6)

Carrier-free (1)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (10)

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Epitope

aa678-753 (8)

aa680-756 (8)

aa655-684 (6)

aa144-193 (4)

aa1454-1744 (4)

aa1100-1350 (2)

Publications

No (62)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (11)

Serum (11)

Tissue Homogenates (3)

Tag

6His, N-terminus (1)

GST, N-terminus (2)

His (1)

His, N-Terminal (1)

His-SUMO (1)

Species

Human (5)

Mouse (1)

Source

E. coli (3)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (1)

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IHC-plus™ Complement C4b Antibody LS-B2888

(4.0) Rating

Antibody:

Complement C4b Chicken anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Complement C4b Antibody (aa655-684) LS-C319943

Antibody:

Complement C4b Rabbit anti-Mouse Polyclonal (aa655-684) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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Complement C4b Antibody (aa655-684, Azide-free, HRP) LS-C253161

Antibody:

Complement C4b Rabbit anti-Mouse Polyclonal (aa655-684) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free

• Unconjugated
• HRP, Azide-free

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Complement C4b Antibody (aa678-753) LS-C293481

Antibody:

Complement C4b Rabbit anti-Mouse Polyclonal (aa678-753) Antibody

Reactivity:

Mouse

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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Complement C4b Antibody (aa678-753, HRP) LS-C709408

Antibody:

Complement C4b Rabbit anti-Mouse Polyclonal (aa678-753) (HRP) Antibody

Reactivity:

Mouse

Format:

HRP Conjugated

Price:

100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557

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Complement C4b Antibody (aa678-753, Biotin) LS-C298887

Antibody:

Complement C4b Rabbit anti-Mouse Polyclonal (aa678-753) (Biotin) Antibody

Reactivity:

Mouse

Format:

Biotin Conjugated

Price:

100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

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Mouse Complement C4b (Sandwich ELISA) ELISA Kit - LS-F8056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Monkey Complement C4b (Sandwich ELISA) ELISA Kit - LS-F42671

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

4.69 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F22486

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

4.688 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$549

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F51574

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$958

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F4550

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F11162

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Complement C4b Antibody (clone 2E3) LS-C196782

Antibody:

Complement C4b Mouse anti-Human Monoclonal (2E3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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Complement C4b Antibody (Biotin) LS-C689699

Antibody:

Complement C4b Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678; 2 ml/$915; 5 ml/$1,541

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Human Complement C4b Protein (Recombinant 6His, N-terminus) (aa1454-1744) - LS-G23217

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

35.1 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human Complement C4b Protein (Recombinant His, N-Terminal) (aa680-756) - LS-G13620

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

12.6 kDa

Price:

50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Complement C4b Antibody (aa1454-1744) LS-C370884

Antibody:

Complement C4b Rabbit anti-Human Polyclonal (aa1454-1744) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Complement C4b Antibody (aa1454-1744, HRP) LS-C370882

Antibody:

Complement C4b Rabbit anti-Human Polyclonal (aa1454-1744) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

Complement C4b Antibody (aa1454-1744, Biotin) LS-C370885

Antibody:

Complement C4b Rabbit anti-Human Polyclonal (aa1454-1744) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

Complement C4b Antibody (aa680-756) LS-B15272

Antibody:

Complement C4b Rabbit anti-Human Polyclonal (aa680-756) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Mouse Complement C4b Protein (Recombinant His) (aa678-753) - LS-G13621

Source:

E. coli

Tag:

His

Molecular Weight:

10.2 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human Complement C4b (Sandwich ELISA) ELISA Kit - LS-F33595

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

4.688 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse Complement C4b (Sandwich ELISA) ELISA Kit - LS-F52940

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

Select

Human Complement C4b Protein (Recombinant GST, N-terminus) (aa1347-1446) - LS-G57939

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human Complement C4b Protein (Recombinant His-SUMO) (aa1454-1744) - LS-G21376

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

49.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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