Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Complement C3
complement component 3
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
| Gene Name: | complement component 3 |
| Synonyms: | C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3 |
| Target Sequences: | NM_000064 NP_000055.2 P01024 |
Publications (8)
1
Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia. Wang W, Irani RA, Zhang Y, Ramin SM, Blackwell SC, Tao L, Kellems RE, Xia Y. Hypertension. 2012 60:712-21. (IHC; Mouse)
[Full Text Article]
[PubMed:22868393]
[PMC:PMC4131740]
Related Antibodies: LS-C22283.
2
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites. Braig D, Nero TL, Koch HG, Kaiser B, Wang X, Thiele JR, Morton CJ, Zeller J, Kiefer J, Potempa LA, Mellett NA, Miles LA, Du XJ, Meikle PJ, Huber-Lang M, Stark GB, Parker MW, Peter K, Eisenhardt SU. Nature communications. 2017 8:14188. (Flo; Human)
[Full Text Article]
[PubMed:28112148]
[PMC:PMC5264208]
Related Antibodies: LS-C62856.
3
Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases. Fridkis-Hareli M, Storek M, Mazsaroff I, Risitano AM, Lundberg AS, Horvath CJ, Holers VM. Blood. 2011 118:4705-13. (Flo; Human)
[Full Text Article]
[PubMed:21860027]
Related Antibodies: LS-C34556.
☰ Filters
Products
Antibodies
(105)
ELISA Kits
(38)
Proteins
(17)
Type
Competitive EIA
(5)
Custom
(1)
Native
(1)
Over-Expression Lysate
(2)
Primary
(105)
Recombinant
(14)
Sandwich
(31)
Sandwich CLIA
(1)
Target
Complement C3
(160)
Reactivity
Human
(77)
Mouse
(29)
Rat
(20)
Bovine
(2)
Canine
(1)
Chicken
(3)
Dog
(2)
Guinea pig
(2)
Monkey
(2)
Pig
(12)
Rabbit
(3)
Sheep
(1)
Application
IHC
(30)
IHC-Fr
(10)
IHC-P
(10)
WB
(74)
Flo
(22)
DD
(1)
ELISA
(54)
ICC
(2)
ID
(1)
IE
(1)
IF
(2)
IP
(1)
Peptide-ELISA
(3)
Turbidimetry
(3)
Host
rabbit
(56)
mouse
(37)
goat
(8)
rat
(1)
sheep
(3)
Product Group
IHCPlus
(3)
Isotype
IgG
(25)
IgG1
(29)
IgG1,k
(2)
IgG2a
(2)
IgG2a,k
(1)
IgG2b
(2)
IgG2b,k
(2)
Clonality
monoclonal mc
(38)
polyclonal pc
(67)
Clone
053A-514.3.1.4
(1)
10-21
(1)
10C7
(4)
11H9
(1)
4C6A8
(1)
5F9
(1)
6C9
(4)
8B5H2
(1)
BH6
(1)
H13
(1)
Format
12 x 8-Well Microstrips
(2)
96-Well Microplate
(7)
96-Well Strip Plate
(29)
APC
(4)
APC Conjugated
(4)
Biotin Conjugated
(13)
Cy3 Conjugated
(4)
Cy7 Conjugated
(4)
FITC Conjugated
(15)
HRP Conjugated
(10)
PE Conjugated
(9)
Serum
(1)
Unconjugated
(46)
Epitope
aa1322-1661
(9)
aa23-300
(8)
aa966-1313
(8)
aa1314-1663
(5)
aa965-1303
(3)
aa1000-1326
(2)
C-Terminus
(1)
aa1580-1592
(1)
aa681-693
(1)
Publications
No
(152)
Yes
(8)
Sample Type
Cell Culture
(1)
Cell Culture Supernatants
(4)
Cell Supernatant
(2)
Milk
(1)
Plasma
(36)
Saliva
(2)
Serum
(36)
Tissue Homogenates
(11)
Urine
(2)
Tag
6His, N-terminus
(1)
6His-SUMO, N-terminus
(1)
GST, N-terminus
(1)
His
(4)
His-S
(1)
His-SUMO
(1)
Myc-DDK (Flag)
(3)
Species
Cow
(1)
Human
(8)
Mouse
(4)
Pig
(1)
Rat
(2)
Source
293T Cells
(1)
E. coli
(11)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Yeast
(1)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(4)
Complement C3 Mouse anti-Human Monoclonal (5F9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Complement C3 Rat anti-Mouse Monoclonal (11H9) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$919
Complement C3 Mouse anti-Human Monoclonal (6C9) Antibody
Human
ELISA, Flo
Unconjugated
250 µg/$478
Complement C3 Mouse anti-Human Monoclonal (PE) (6C9) Antibody
Mouse, Human
ELISA, Flo
PE Conjugated
50 µg/$382
Complement C3 Rabbit anti-Pig Polyclonal (aa23-300) Antibody
Pig
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
Complement C3 Goat anti-Human Polyclonal (aa1580-1592) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
Complement C3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Complement C3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
Complement C3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Complement C3 Mouse anti-Mouse Monoclonal (Biotin) (10C7) Antibody
Mouse, Human
ELISA, Flo
Biotin Conjugated
100 µg/$380
Complement C3 Mouse anti-Human Monoclonal (Biotin) (6C9) Antibody
Mouse, Human
ELISA, Flo
Biotin Conjugated
100 µg/$380
Complement C3 Mouse anti-Human Monoclonal (PE) (10C7) Antibody
Human
ELISA, Flo
PE Conjugated
50 µg/$383
Complement C3 Mouse anti-Human Monoclonal (FITC) (6C9) Antibody
Mouse, Human
ELISA, Flo
FITC Conjugated
100 µg/$402
Complement C3 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Complement C3 Mouse anti-Human Monoclonal (FITC) (10C7) Antibody
Human
Flo
FITC Conjugated
100 µg/$402
Complement C3 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Strip Plate
Human
0.02 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture, Milk, Plasma, Saliva, Serum, Urine
1 Plate/$699
Sandwich
96-Well Strip Plate
Mouse
0.2 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$850
Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich
96-Well Strip Plate
Rat
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
Sandwich
96-Well Microplate
Mouse
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Microplate
Human
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$724
Sandwich
96-Well Strip Plate
Human
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$537
Sandwich
96-Well Microplate
Rat
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Microplate
Pig
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
Viewing 1-25
of 160
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
