Complement C2

complement component 2

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

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Products

Antibodies (51)

ELISA Kits (14)

Proteins (13)

Type

Competitive EIA (1)

Custom (3)

Over-Expression Lysate (4)

Primary (51)

Recombinant (9)

Sandwich (10)

Target

Complement C2 (78)

Reactivity

Human (49)

Mouse (9)

Rat (17)

Bovine (3)

Chicken (1)

Chimpanzee (6)

Dog (3)

Gibbon (3)

Hamster (7)

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Monkey (7)

Orangutan (6)

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IHC (7)

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ID (1)

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SDS-PAGE (3)

Host

rabbit (43)

mouse (8)

Product Group

IHCPlus (3)

Isotype

IgG (24)

IgG1 (4)

IgG1,k (1)

IgG2a,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (9)

polyclonal pc (42)

Clone

014 (1)

06 (1)

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OTI12G10 (2)

OTI1A7 (2)

Format

12 x 8-Well Microstrips (1)

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Epitope

aa245-451 (8)

aa473-723 (8)

aa147-176 (7)

aa201-250 (4)

aa398-447 (4)

aa469-752 (4)

aa265-642 (1)

Publications

No (78)

Sample Type

Cell Supernatant (1)

Plasma (8)

Serum (8)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His,C-terminus (2)

His-T7 (1)

Human IgG Fc, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (9)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (6)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (5)

Biologically Active

Biologically active (1)

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IHC-plus™ Complement C2 Antibody LS-B15582

(4.0) Rating

Antibody:

Complement C2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Complement C2 Antibody (aa245-451) LS-C293468

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa245-451) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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Complement C2 Antibody (aa398-447) LS-C31855

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa398-447) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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Complement C2 Antibody (aa398-447, HRP) LS-C442389

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa398-447) (HRP) Antibody

Reactivity:

Mouse, Dog, Pig, Horse, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP

• Unconjugated
• HRP

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Complement C2 Antibody (aa201-250) LS-C80448

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa201-250) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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Complement C2 Antibody (aa201-250, FITC) LS-C442556

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa201-250) (FITC) Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Horse, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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Mouse Complement C2 (Sandwich ELISA) ELISA Kit - LS-F18548

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat Complement C2 Protein (Recombinant 6His, N-terminus) (aa473-723) - LS-G24148

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

31.6 kDa

Price:

10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192

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Rat Complement C2 (Sandwich ELISA) ELISA Kit - LS-F25243

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.188 - 12 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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IHC-plus™ Complement C2 Antibody (clone 5C3) LS-B15378

(4.0) Rating

Antibody:

Complement C2 Mouse anti-Human Monoclonal (5C3) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Complement C2 Antibody (aa147-176, Biotin) LS-C208173

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa147-176) (Biotin) Antibody

Reactivity:

Hamster, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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Complement C2 Antibody (aa147-176, Azide-free, HRP) LS-C208175

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa147-176) (Azide-free) (HRP) Antibody

Reactivity:

Hamster, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Biotin
• HRP, Azide-free

• Biotin
• HRP, Azide-free

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Human Complement C2 (Sandwich ELISA) ELISA Kit - LS-F5291

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$764

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IHC-plus™ Complement C2 Antibody LS-B2639

(4.0) Rating

Antibody:

Complement C2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$485

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Complement C2 Antibody (clone 7G1) LS-C196781

Antibody:

Complement C2 Mouse anti-Human Monoclonal (7G1) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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Complement C2 Antibody LS-C309661

Antibody:

Complement C2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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Complement C2 Antibody LS-C147764

Antibody:

Complement C2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID

Format:

Unconjugated

Price:

1 ml/$459

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Mouse Complement C2 Protein (Recombinant His,C-terminus) (Met1-Leu760) - LS-G49171

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse C2 comprises 752 amino acids and has a predicted molecular mass of 84.2 kDa. The apparent molecular mass of the protein is approximately 91.2 kDa in SDS-PAGE under reducing conditions.

Price:

20 µg/$317

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Complement C2 Antibody (clone 014, Preservative Free) LS-C820645

Antibody:

Complement C2 Rabbit anti-Human Monoclonal (Preservative Free) (014) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

20 µl/$271; 100 µl/$412

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Monkey Complement C2 (Sandwich ELISA) ELISA Kit - LS-F42651

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Complement C2 Antibody (aa469-752, clone OTI12G10) LS-C800055

Antibody:

Complement C2 Mouse anti-Human Monoclonal (aa469-752) (OTI12G10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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Complement C2 Antibody (aa469-752, clone OTI12G10, Carrier-free) LS-C791140

Antibody:

Complement C2 Mouse anti-Human Monoclonal (aa469-752) (Carrier-free) (OTI12G10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

Complement C2 Antibody (aa469-752, clone OTI1A7) LS-C793997

Antibody:

Complement C2 Mouse anti-Human Monoclonal (aa469-752) (OTI1A7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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Complement C2 Antibody (aa469-752, clone OTI1A7, Carrier-free) LS-C799585

Antibody:

Complement C2 Mouse anti-Human Monoclonal (aa469-752) (Carrier-free) (OTI1A7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

Complement C2 Antibody (aa265-642) LS-C185703

Antibody:

Complement C2 Rabbit anti-Human Polyclonal (aa265-642) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µl/$450

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