COMP / THBS5

cartilage oligomeric matrix protein

May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

COMP / THBS5 (10)

Publications

No (10)

Tag

His (6)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (3)

Rat (2)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Human Cells (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human COMP / THBS5 Protein (Recombinant His) (Met1-Ala757) - LS-G97069

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

82.4 kDa

Price:

100 µg/$721

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Human COMP / THBS5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65180

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.9 kDa

Price:

20 µg/$1,107

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Rat COMP / THBS5 Protein (Recombinant His) (aa235-423) - LS-G13469

Source:

E. coli

Tag:

His

Molecular Weight:

22.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

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Mouse COMP / THBS5 Protein (Recombinant His) (aa40-180) - LS-G13460

Source:

E. coli

Tag:

His

Molecular Weight:

16.4 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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Mouse COMP / THBS5 Protein (Recombinant His) (aa554-753) - LS-G13455

Source:

E. coli

Tag:

His

Molecular Weight:

24.5 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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Rat COMP / THBS5 Protein (Recombinant His) (aa35-179) - LS-G13466

Source:

E. coli

Tag:

His

Molecular Weight:

17.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

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Mouse COMP / THBS5 Protein (Recombinant His) (aa317-455) - LS-G13468

Source:

E. coli

Tag:

His

Molecular Weight:

16.7 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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Human COMP / THBS5 Protein (Recombinant His-T7) (aa123-240) - LS-G24234

Source:

E. coli

Tag:

His-T7

Molecular Weight:

16.5 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human COMP / THBS5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75015

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.86 kDa

Price:

20 µg/$150

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COMP / THBS5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123397

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.86 kDa

Price:

100 µg/$494

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