Collagen I

Type I collagen is the most abundant collagen of the human body which forms large, eosinophilic fibers known as collagen fibers. It is present in scar tissue, the end product when tissue heals by repair, as well as tendons, ligaments, the endomysium of myofibrils, the organic part of bone, the dermis, the dentin and organ capsules. Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is encoded by the COL1A1 gene. Collagen alpha-2(I) chain is encoded by the COL1A2 gene. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for alpha-1 type I collagen since alpha-2 is less abundant. Multiple messages for this gene result from multiple polyadenylation signals, a feature shared by most of the other collagen genes.

Collagen I Target Details

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Proteins (5)

Type

Native (4)

Recombinant (1)

Target

Collagen I (5)

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No (5)

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His (1)

Species

Bovine (1)

Human (2)

Mouse (1)

Rat (1)

Source

Bovine (1)

E. coli (1)

Human (1)

Mouse (1)

Rat (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Mouse Collagen I Protein (Native) - LS-G136198

Source:

Mouse

Tag:

None

Molecular Weight:

~300 kDa

Price:

0.5 mg/$382

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Bovine Collagen I Protein (Native) - LS-G136163

Source:

Bovine

Tag:

None

Molecular Weight:

~300 kDa

Price:

10 mg/$367

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Rat Collagen I Protein (Native) - LS-G136239

Source:

Rat

Tag:

None

Price:

10 mg/$411

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Human Collagen I Protein (Native) - LS-G136166

Source:

Human

Tag:

None

Molecular Weight:

300 kDa

Price:

0.1 mg/$533

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Human Collagen I Protein (Recombinant His) (aa46-134) - LS-G141126

Source:

E. coli

Sequence Length:

89 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

9.79 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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