Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Gene Name: | collagen, type VI, alpha 1 |
Family/Subfamily: | Collagen , not assigned-Collagen |
Synonyms: | COL6A1, Alpha 1 (VI) chain (61 AA), Collagen alpha-1(VI) chain, Collagen alpha 1(vi), OPLL, Collagen, type VI, alpha 1 |
Target Sequences: | NM_001848 NP_001839.2 P12109 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.